On July 26th we are back with three new and amazing topics. Don’t forget to like our page Seattle Science Slam to stay up to date.
PhD student in the Pathobiology Program at UW
«Host-pathogen interactions: the model matters»
Scientists use animal models to study how microbes make us sick. The models we use to study these pathogens can affect our understanding of what happens during an infection. My research focuses on the bacteria that causes typhoid fever, Salmonella enterica serovar Typhi, which can only infect humans. To study typhoid fever, scientists have used a similar but different type of Salmonella to infect mice – what are we missing by not studying the real pathogen?
Research Scientist at the UW Kidney Research Institute
«Nanoengineered Muscular Thin Films for Drug-Induced Cardiotoxicity Screening»
New medicines save lives, but they can also come with some pretty serious side effects. Irregular heartbeat. Chest pain. Even death. Scientists already test every new drug using engineered human cells lines to try to see if it does more harm than good, but these tests only go so far. It turns out heart cells grown in the lab are pretty different from an actual, beating heart. My research is aimed at improving the predictive value of drug screening by creating well developed cardiac tissue made of matured human stem cells.
Domnita Valeria Rusnac
PhD candidate in the department of Pharmacology at UW
«Proteins, drugs, and degradation»
Like cities, our cells are busy places. Their insides buzz with constant activity – molecules get built up, molecules get broken down. Proteins, the fascinating molecular machines that run our cells, are usually well behaved… but sometimes they get out of hand. Misbehaving proteins are the cause of many serious diseases. My work is focused on trying to hijack the process of degradation within the cell, in order to break down problematic proteins.